研究领域
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课题组拟开展的研究内容:
开发过渡金属催化糖基交叉偶联反应的新方法
发展无保护糖类精准定点修饰的新策略
合成具有重要生物活性的寡糖和糖缀合物
开发多肽与蛋白质化学修饰的新方法与新策略
开展糖类的药物化学及化学生物学研究
论文成果 MORE+
- · Umpolung Ala(B) Reagents for the Synthesis of Non-Proteogenic Amino Acids, Peptides and Proteins.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.2022
- · Recent advances in glycosylation involving novel anomeric radical precursors.JOURNAL OF CARBOHYDRATE CHEMISTRY.2022
- · Recent Advances in Transition-Metal-Catalyzed Glycosyl Cross-Coupling Reactions.Chem Catalysis.2022
- · Organometallic AlaM Reagents for Umpolung Peptide Diversification.Chem Catalysis .2021
- · Stereoretentive C(sp3)-S Cross-Coupling.J. Am. Chem. Soc..2018
- · Stereoselective Oxidative Glycosylation of Anomeric Nucleophiles with Alcohols and Carboxylic Acids.Nat. Commun. .2018
- · Stereochemistry of Transition Metal Complexes Controlled by the Metallo-Anomeric Effect.J. Am. Chem. Soc..2020
- · Catalytic and Photochemical Strategies to Stabilized Radicals Based on Anomeric Nucleophiles.J. Am. Chem. Soc..2020
- · Acyl Glycosides Through Stereospecific Glycosyl Cross-Coupling - Rapid Access to C(sp3)-Linked Glycomimetics.ACS Cent. Sci..2018
- · Stereoretentive Reactions at the Anomeric Position: Synthesis of Selenoglycosides.Angew. Chem. Int. Ed..2018
专利
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著作成果
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