研究领域：

论文成果： More>>

• Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel-Lindau protein .Oncogene .2020
• Deficiency of Histone Methyltransferase SET Domain-Containing 2 in Liver Leads to Abnormal Lipid Metabolism and HCC .HEPATOLOGY .2021
• The histone methyltransferase Setd2 is indispensable for V(D)J recombination. .Nat. Commun. .2019
• Deficiency of Histone Methyltransferase SET Domain-Containing 2 in Liver Leads to Abnormal Lipid Metabolism and HCC .HEPATOLOGY .2021
• Multilevel Regulation of beta-Catenin Activity by SETD2 Suppresses the Transition from Polycystic Kidney Disease to Clear Cell Renal Cell Carcinoma .CANCER RESEARCH .2021
• Histone Lysine Methyltransferase SETD2 Regulates Coronary Vascular Development in Embryonic Mouse Hearts .FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY .2021
• SETD2 is essential for terminal differentiation of erythroblasts during fetal erythropoiesis .BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS .2021
• The histone methyltransferase SETD2 modulates oxidative stress to attenuate experimental colitis .REDOX BIOLOGY .2021
• Loss of Setd2 associates with aberrant microRNA expression and contributes to inflammatory bowel disease progression in mice .GENOMICS .2021
• SETD2 epidermal deficiency promotes cutaneous wound healing via activation of AKT/mTOR Signalling .CELL PROLIFERATION .2021

科研项目： More>>

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• 组蛋白甲基化酶Setd2通过影响WNT/β-catenin信号途径抑制肾癌的作用机制研究 -2024/12/01
• 组蛋白甲基化酶Setd2通过影响WNT/β-catenin信号途径抑制肾癌的作用机制研究 -2024/12/01
• 生物医学有机废弃物的新型降解技术开发 -2022/12/01
• 肿瘤淋巴转移动物模型开发 -2021/07/01
• SetD2/H3K36me3缺陷型肾癌小鼠模型的建立和应用 -2022/04/01
• SetD2/H3K36me3缺陷型肾癌小鼠模型的建立和应用 -2022/04/01
• 雄性不育SetD2基因敲除小鼠模型的建立和分析 -2021/04/01