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Scientific Research
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Paper Publications
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Engineering of Reductive Aminases for Asymmetric Synthesis of Enantiopure Rasagiline.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY.2021
酵母脂肪酶分子进化及催化合成(S)-1,4-苯并二噁烷.中国生物工程杂志.2022
鲍曼不动杆菌UDP-葡萄糖4-差向异构酶Gne1的表征.中国药科大学学报.2021
Molecular Evolution of an Aminotransferase Based on Substrate–Enzyme Binding Energy Analysis for Efficient Valienamine Synthesis.ACS Catalysis.2022
Remodeling enzyme active sites by stepwise loop insertion.ENZYME ENGINEERING AND EVOLUTION: GENERAL METHODS.2020
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Published Books
Chapter Five - Remodeling enzyme active sites by stepwise loop insertion, Methods in Enzymology, 2020, 643, 111-127.
酶定向分子进化:拓展生物催化和生物转化的功能空间（《微生物基因组学及合成生物学进展》第四部分第四篇）
Research Projects
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海洋嗜油菌L-苏氨酸醛缩酶产物立体选择性机制解析及活性中心再设 计-2026-12-01
产井冈霉烯胺菌种改造及工艺优化-2026-10-01
多手性中心C7N环醇胺类化合物生物合成体系的精准构筑-2023-12-01
氨基糖苷类化合物生物合成元件的募集表征-2024-06-01
基于化学生物学“凸凹互补”原理的工程化酶的设计与表达-2024-07-01
