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Scientific Research
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Scientific Research
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Chromatin jets define the properties of cohesin-driven in vivo loop extrusion.Molecular Cell.2022
Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery.NATURE COMMUNICATIONS.2022
3D chromosomal landscape reveals miR-146a dysfunctional enhancer in lupus and establishes a CRISPR-mediated approach to inhibit the IFN pathway.Arthritis & Rheumatology.2023
Identification of Two Subsets of Subcompartment A1 Associated with High Transcriptional Activity and Frequent Loop Extrusion.Biology (Basel).2023
Chromatin jets define the properties of cohesin-driven in vivo loop extrusion.Molecular Cell.2022
CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function.Cell.2015
CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice.Proc. Natl. Acad. Sci. U.S.A..2012
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基因组CTCF识别位点体外结合特征分析和在体调用的分子机制研究
三维基因表达调控机制整合研究, Provincial municipal and autonomous regional science and technology projects
基因组CTCF识别位点体外结合特征分析和在体调用的分子机制研究, National Natural Science Foundation of China (NSFC)
转录因子CTCF指导3D基因组构建的分子机制研究
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