上海交大研究生院主页平台管理系统侯四化--中文主页--科学研究

所在单位：药学院
职称：副教授
电子邮箱：housihua@sjtu.edu.cn
教师拼音名称：housihua
办公地点：药学院7号楼502
在职信息：在职

科学研究

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Si-Hua Hou, Yong-Qiang Tu,* Lin Liu, Fu-Min Zhang, Shao-Hua Wang,* Xiao-Ming Zhang, Divergent and Efficient Syntheses of the Lycopodium Alkaloids (–)-Lycojaponicumin C, (–)-8-Deoxyserratinine, (+)-Fawcettimine, and (+)-Fawcettidine. Angew. Chem. Int. Ed. 2013, 52, 11373 –11376.
Si-Hua Hou, Yong-Qiang Tu,* Shuang-Hu Wang, Chao-Chao Xi, Fu-Min Zhang, Shao-Hua Wang, Yan-Tao Li, Lin Liu, Total Syntheses of the Tetracyclic Cyclopiane Diterpenes Conidiogenone, Conidiogenol, and Conidiogenone B. Angew. Chem. Int. Ed. 2016, 55, 4456 – 4460.
Si-Hua Hou, Adriana Y. Prichina, Mengxi Zhang, Guangbin Dong,* Asymmetric Total Syntheses of Di- and Sesqui-Terpenoids via Catalytic C–C Activation of Cyclopentanones. Angew. Chem. Int. Ed. 2020, 59, 7848 – 7856.
Si-Hua Hou, Xuan Yu, Rui Zhang, Lin Deng, Mengxi Zhang, Adriana Y. Prichina, Guangbin Dong,* Enantioselective Intramolecular Type II-Cycloaddition of Alkynes via C−C Activation of Cyclobutanones: Rapid and Asymmetric Construction of [3.3.1] Bridged Bicycles. J. Am. Chem. Soc. 2020, 142, 13180-13189.
Si-Hua Hou, Adriana Y. Prichina, Guangbin Dong,* Deconstructive Asymmetric Total Synthesis of Morphine-Family Alkaloid (–)-Thebainone A. Angew. Chem. Int. Ed. 2021, 60, 13057 – 13064.
Quan-Zhe Li,# Si-Hua Hou,# Jin-Chen Kang, Peng-Fei Lian, Yu Hao, Chao Chen, Jia Zhou, Tong-Mei Ding, Shu-Yu Zhang*. Bioinspired Palladium-Catalyzed Intramolecular C(sp3)−H Activation for the Collective Synthesis of Proline Natural Products. Angew. Chem. Int. Ed. 2022, 61, e202207088. (# contributed equally).
Si-Hua Hou,# Xuan Yu,# Rui Zhang, Cole Wagner, Guangbin Dong,* Rhodium-Catalyzed Diastereo- and Enantioselective Divergent Annulations between Cyclobutanones and 1,5-Enynes: Rapid Construction of Complex C(sp3)‑Rich Scaffolds. J. Am. Chem. Soc. 2022, 144, 22159 – 22169. (# contributed equally).
Jun-Jie Yin, Yun-Peng Wang, Jun Xue, Feng-Fan Zhou, Xing-Qian Shan, Rong Zhu, Kun Fang, Lei Shi*, Shu-Yu Zhang, Si-Hua Hou*, Wujiong Xia, and Yong-Qiang Tu* Total Syntheses of Polycyclic Diterpenes Phomopsene, Methyl Phomopsenonate, and iso-Phomopsene via Reorganization of C–C Single Bonds. J. Am. Chem. Soc. 2023, 145, 21170-21175
Kun Fang, Bao-Heng Dou, Fu-Min Zhang*, Yun-Peng Wang, Zi-Rui Shan, Xiao-Yu Wang, Si-Hua Hou, Yong-Qiang Tu*, Tong-Mei Ding, Expansion of Structure Property in Cascade Nazarov Cyclization and Cycloexpansion Reaction to Diverse Angular Tricycles and Total Synthesis of Nominal Madreporanone Angew. Chem. Int. Ed. 2025, 63, e202412337
Yuan Xue, Si-Hua Hou*, Xiang Zhang, Fu-Min Zhang, Xiao-Ming Zhang, Yong-Qiang Tu* Total Synthesis of the Hexacyclic Sesterterpenoid Niduterpenoid B via Structural Reorganization Strategy. J. Am. Chem. Soc. 2024, 146, 25445−25450

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