研究领域：

论文成果： More>>

• An Atypical Acyl-CoA Synthetase Enables Efficient Biosynthesis of Extender Units for Engineering a Polyketide Carbon Scaffold .Angew Chem Int Ed Engl .2022
• A Dual Role Reductase from Phytosterols Catabolism Enables the Efficient Production of Valuable Steroid Precursors .Angewandte Chemie International Edition .2021
• A Permissive Medium Chain Acyl-CoA Carboxylase Enables the Efficient Biosynthesis of Extender Units for Engineering Polyketide Carbon Scaffolds .ACS Catalysis .2021
• 亚胺还原酶在手性胺合成中的应用 .合成生物学 .2022
• A Pair of Atypical KAS III Homologues with Initiation and Elongation Functions Program the Polyketide Biosynthesis in Asukamycin .Angewandte Chemie Interantional Edition .2022
• Engineering Imine Reductase for Efficient Biosynthesis of 1-Aryl-Tetrahydro-beta-Carbolines and Their N-Methylation Products .ACS CATALYSIS .2022
• Expanding the Chemical Diversity of Fasamycin Via Genome Mining and Biocatalysis .JOURNAL OF NATURAL PRODUCTS .2022
• Norditerpenoids biosynthesized by variediene synthase-associated P450 machinery along with modifications by the host cell Aspergillus oryzae .Synthetic and Systems Biotechnology .2022
• Emerging diversity in polyketide synthase .Tetrahedron Letters .2022
• Biosynthesis of pyrroloindoline-containing natural products .NATURAL PRODUCT REPORTS .2022

科研项目：

• 氢化可的松生物催化技术开发 -2025/06/01
• 酰基辅酶A羧化酶的理性设计及在聚酮骨架编辑中的应用 -2026/03/01
• 芳香聚酮骨架的生物合成 -2025/08/01
• 复杂吡咯并吲哚生物碱的生物合成 -2026/12/01
• 芳香聚酮骨架的生物合成 -2025/08/01
• 抗真菌药物UK-2A的组合生物合成研究 -2023/12/01
• 11β羟黄体酮生物催化 -2022/12/01