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Paper Publications
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Expanding horizons of CRISPR applications beyond genome editing.Trends Genet..2025
Rational spatial rewiring of key enzymes enhances α-santalene production in Saccharomyces cerevisiae.Bioresour. Technol..2025
STAGE: A compact and versatile TnpB-based genome editing toolkit for Streptomyces.Proc. Natl. Acad. Sci. U.S.A..2025
Programmable probiotics as next-generation living therapeutics: bridging synthetic biology and precision medicine.Curr. Opin. Biotechnol..2025
CRISPy-web 3.0: a unified platform for multi-modal guide RNA design for CRISPR and TnpB genome editing applications.Synth. Syst. Biotechnol..2025
Patents
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CRISPy-web软件第3版
一种用于链霉菌的高效基因编辑系统及其构建方法和应用
一种适用于链霉菌的TnpB基因编辑系统及其构建和应用
基于偶联TnpB和重构NHEJ的链霉菌迷你基因编辑系统及其构建方法和应用
一种用于链霉菌的高效单碱基编辑工具及其构建方法和应用
Published Books
CRISPR-Cas9 Toolkit for Actinomycete Genome Editing
Research Projects
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新型高效精准紧凑型放线菌基因编辑系统开发-2027-11-01
新型链霉菌通用培养基的配方优化改良-2025-12-01
同基因型链霉菌群体间领地意识形成的分子机制研究-2027-12-01
DNA硫修饰及全新基因编辑体系-2024-10-01
智能化微生物基因组信息挖掘平台的创建,自然科学-2022-12-01