研究领域
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论文成果 MORE+
- · Optogenetic tools for microbial synthetic biology.BIOTECHNOLOGY ADVANCES.2022
- · Activating cryptic biosynthetic gene cluster through a CRISPR-Cas12a-mediated direct cloning approach.NUCLEIC ACIDS RESEARCH.2022
- · Hyper-Synergistic Antifungal Activity of Rapamycin and Peptide-Like Compounds against Candida albicans Orthogonally via Tor1 Kinase.ACS Infectious Diseases.2021
- · Integrating PCR-free amplification and synergistic sensing for ultrasensitive and rapid CRISPR/Cas12a-based SARS-CoV-2 antigen detection.Synthetic and Systems Biotechnology.2021
- · A versatile genetic engineering toolkit for E. coli based on CRISPR-prime editing.NATURE COMMUNICATIONS.2021
- · Metabolic engineering of antibiotic factories: New tools for antibiotic production in actinomycetes.Trends in Biotechnology .2015
- · Trichodermaketones A-D and 7-O-methylkoninginin D from the marine fungus Trichoderma koningii.Journal of Natural Products.2010
- · CRISPR-nRAGE, a Cas9 nickase-reverse transcriptase assisted versatile genetic engineering toolkit for E. coli.BioRxiv.2020
- · CRISPR-Cas9-based, CRISPRi, and CRISPR-BEST-mediated genetic manipulation in streptomycetes.Nature Protocols.2020
- · CRISPR/Cas-based genome engineering in natural product discovery.Natural Product Reports.2018
专利
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科研项目 MORE+
- · 新型链霉菌通用培养基的配方优化改良-2025/12/01
- · 同基因型链霉菌群体间领地意识形成的分子机制研究-2027/12/01
- · DNA硫修饰及全新基因编辑体系-2024/10/01
- · 智能化微生物基因组信息挖掘平台的创建-2022/12/01
- · 微生物合成生物学使能技术-2024/12/01
- · 特殊环境地盘细胞构建的先进使能技术-2026/11/01
- · 无需启动子的细菌基因转录激活系统的构建-2025/12/01
- · 底盘/异源途径适配性表达使能技术-2024/06/01
- · CRISPR-Cas9 toolkit development and application in actinomycetes for new antibiotics discovery-2017/10/01
- · 合成微生物体系的适配性研究-2017/12/01