研究领域
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论文成果 MORE+
- · Structural basis of Streptomyces transcription activation by zinc uptake regulator.NUCLEIC ACIDS RESEARCH.2022
- · Endowing homodimeric carbamoyltransferase GdmN with iterative functions through structural characterization and mechanistic studies.Nature Communications.2022
- · The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases.COMMUNICATIONS BIOLOGY.2022
- · Structural visualization of transient interactions between the cis-acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase.ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY.2022
- · Structural Insight of KSIII (β-Ketoacyl-ACP Synthase)-like Acyltransferase ChlB3 in the Biosynthesis of Chlorothricin.Molecules.2022
- · Structural basis of Streptomyces transcription activation by zinc uptake regulator.NUCLEIC ACIDS RESEARCH.2022
- · Structural and Mechanistic Insights into Chain Release of the Polyene PKS Thioesterase Domain.ACS CATALYSIS.2022
- · Crystal structure of Acetyl-CoA carboxylase (AccB) from Streptomyces antibioticus and insights into the substrate-binding through in silico mutagenesis and biophysical investigations.COMPUTERS IN BIOLOGY AND MEDICINE.2022
- · Substrate-bound structures of a ketoreductase from amphotericin modular polyketide synthase.JOURNAL OF STRUCTURAL BIOLOGY.2018
- · Stereospecificity of Enoylreductase Domains from Modular Polyketide Synthases.ACS CHEMICAL BIOLOGY.2018
专利
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科研项目 MORE+
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- · 聚酮天然产物生物合成的结构生物学解析-2016/11/01
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- · 聚酮合成起始单元选择的分子机制研究-2019/12/01
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