研究领域
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合成生物学，CRISPR基因编辑，生物制造，未来生物技术
论文成果 MORE+
- · Expanding horizons of CRISPR applications beyond genome editing.Trends Genet..2025
- · Rational spatial rewiring of key enzymes enhances α-santalene production in Saccharomyces cerevisiae.Bioresour. Technol..2025
- · STAGE: A compact and versatile TnpB-based genome editing toolkit for Streptomyces.Proc. Natl. Acad. Sci. U.S.A..2025
- · Programmable probiotics as next-generation living therapeutics: bridging synthetic biology and precision medicine.Curr. Opin. Biotechnol..2025
- · CRISPy-web 3.0: a unified platform for multi-modal guide RNA design for CRISPR and TnpB genome editing applications.Synth. Syst. Biotechnol..2025
- · Halogenases and dehalogenases: mechanisms, engineering, and applications.Nat. Prod. Rep..2025
- · Systems Analysis of Highly Multiplexed CRISPR-Base Editing in Streptomycetes.Acs Synthetic Biology.2023
- · Optogenetic tools for microbial synthetic biology.BIOTECHNOLOGY ADVANCES.2022
- · Activating cryptic biosynthetic gene cluster through a CRISPR-Cas12a-mediated direct cloning approach.NUCLEIC ACIDS RESEARCH.2022
- · Hyper-Synergistic Antifungal Activity of Rapamycin and Peptide-Like Compounds against Candida albicans Orthogonally via Tor1 Kinase.ACS Infectious Diseases.2021
专利
科研项目 MORE+
- · 新型高效精准紧凑型放线菌基因编辑系统开发-2027/11/01
- · 新型链霉菌通用培养基的配方优化改良-2025/12/01
- · 同基因型链霉菌群体间领地意识形成的分子机制研究-2027/12/01
- · DNA硫修饰及全新基因编辑体系-2024/10/01
- · 智能化微生物基因组信息挖掘平台的创建-2022/12/01
- · 微生物合成生物学使能技术-2024/12/01
- · 特殊环境地盘细胞构建的先进使能技术-2026/11/01
- · 无需启动子的细菌基因转录激活系统的构建-2025/12/01
- · 底盘/异源途径适配性表达使能技术-2024/06/01
- · CRISPR-Cas9 toolkit development and application in actinomycetes for new antibiotics discovery-2017/10/01